Clinical data for our 5 patients and 82 cases from the medline search were pooled and factors associated with mortality were sought among age, gender, presence of cardiac or pulmonary complications, and doses of thyroid hormone by multiple. Take your hr comms to the next level with prezi video. Bradicardia hipoventilacin hipotermia y, ocasionalmente convulsiones. Among the unleashing factors found are sepsis, exposure to cold, acute. The typical progression is lethargy evolving into stupor and, eventually. Some symptoms of myxedema coma include fatigue, lethargy, depression, dry skin, and weight gain. The deadly manifestation of hypothyroidism is myxedema.
Pdf free download flatform start research documents. Factors associated with mortality of myxedema coma. Hypothyroidism is a very common, yet often overlooked disease. Articulo especial coma mixedematoso resena historica. Untreated or unrecognized hypothyroidism may progress to severe decompensated hypothyroidism or myxedema coma. Definizione ed epidemiologia sindrome clinica dovuta ad insufficiente produzione o secrezione di ormoni tiroidei rallentamento di tutti i processi metabolici. Case report an atypical case of myxedema coma with. An atypical case of myxedema coma with concomitant.
Ipotiroidismo e coma mixedematoso in pronto soccorso. Coma mixedematoso national college enfermeria nurs3040 winter 2017 coma mixedematoso. Most patients, however, are not comatose, and the entity rather represents a form of very severe, decompensated hypothyroidism. Myxedema coma is a rare lifethreatening clinical condition in patients with longstanding severe untreated hypothyroidism, in whom adaptive mechanisms fail to maintain homeostasis. Relatively few cases are reported in the literature since the first case was apparently reported from the st. Coma mixedematoso urgencias y otras situaciones especiales. It can have a myriad of signs and symptoms, and is often nonspecific. We report a case of a 5yearold girl transferred to a tertiary care pediatric emergency department. It is a medical emergency with a high mortality rate.
The term myxedema coma is generally seen as misleading since most patients do not initially present in a coma. Myxedema coma or myxedema crisis is a lifethreatening complication of hypothyroidism. Memorias simposio actualizacion endocrinologia medicas uis 2015. Pdf hypothyroidism is a frequently diagnosed and simply treated disease. Infrequently, patients will present with myxedema coma, characterized by hypothermia, hypotension, bradycardia, and altered mental status in the setting of severe hypothyroidism.
If not recognised, however, in time it may develop into the most severe manifestation of hypothyroidism known as myxedema coma. Broadway, yonkers, ny, usa lake erie college of osteopathic medicine, w grandview blvd, erie, pa, usa. An atypical case of myxedema coma with concomitant nonconvulsive seizure pratikpatel, 1 mikhaelbekkerman, 1,2 cristinavarallorodriguez, 1 andrajendrarampersaud 3 department of medicine, st. Myxedema coma definition, symptoms, causes, treatment. The typical characteristics of myxedema coma, including bradycardia, hypotension, and hypothermia, were absent in this case. Mild myxedema coma usually is treated by a general practitioner or internist while moderate to severe myxedema coma is treated and managed by an endocrinologist. Childhood cases of myxedema coma are extremely rare. Fortunately, it is now a rare presentation of hypothyroidism, likely due to earlier diagnosis as a result of the widespread. The diagnosis of myxedema coma was made based on the patients clinical presentation and a score of 65 on the diagnostic scoring system published in 2014 by popoveniuc et al. Hypothyroidism is a prevalent condition in the general population that is treatable with appropriately dosed thyroid hormone replacement medication. Myxedema coma is defined as severe hypothyroidism leading to decreased mental status, hypothermia, and other symptoms related to slowing of function in multiple organs.
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